The 10 Best CBD Oil Brands for Pain Relief [2022 Update]

CBD Oil for Pain Relief

We know through numerous studies that cannabis (i.e. medical marijuana) can be used as a substitute for prescription painkillers. Of course, the psychoactive effects associated with marijuana make it unappealing for many users.

Cannabidiol (CBD), a non-psychoactive cannabis extract, is also used for a variety of medical conditions - including pain relief. We are seeing that some of the best CBD oils may have a positive impact in terms of pain management.

However, it's important to remind readers that CBD oil isn't approved by the U.S. Food and Drug Administration (FDA) for pain management. This means that the products and statements made in this article are also not evaluated by the FDA. Therefore, they are not intended to diagnose, treat, cure, or prevent any disease or medical condition.

Even without the FDA’s review, however, CBD has received a significant amount of attention. You've likely seen featured stories on top news networks, or have seen/read about CBD being recommended by high profile social figures for various forms of pain relief.

Charlotte's Web, a company branded by Yahoo Finance as "the world’s leading CBD brand by market share," has been featured numerous times in the media on sites such as CNN and The Wall Street Journal , as well as in popular fitness magazines like Men's Health .

CBD is one of the most fascinating additives or isolate we have discovered in recent years. Whereas most pharmaceutical medications focus on the symptoms or one enzyme or channel of the human body, CBD aids in helping a system to function more efficiently. The endocannabinoid system.

So what are the benefits of cbd oil for pain?

Most of the best CBD oil drops you'll find on the market today are effective -- and very easy to take. You simply place a few drops under your tongue, and the CBD absorbs into your system via sublingual blood vessels (exact consumption methods should be written on the CBD oil package you buy; always consult these prior to taking CBD).

CBD oil has been known to help with other conditions aside from - or even related to - pain. For example, many folks suffering from depression, anxiety, and chronic stress have experienced health-related boosts after taking CBD. And of course, many people with chronic pain claim that CBD oil helps them sleep at night.

While CBD oil is not as of yet an FDA-recognized drug for pain management, it is improving the lives of tens of thousands across the country. Here are a few reader-submitted statements regarding the effects of CBD on day-to-day pain:

“I have been suffering from chronic pain in my legs for years. I often find it hard to sleep. CBD oil helps with the pain management, especially as it is impossible to obtain marijuana in my state.” – Kate Summers, Ohio

“I find the amount I’m taking has helped me a lot with my chronic low back pain and aching knees. I am taking far fewer opioids than before, and CBD oil has got me back on track.” – Jeff Freedman, New Jersey

“I had never even heard about CBD oil up until a couple of months ago. Since I’ve started treatment it has changed my life. Thank you for all the help and good vibes!!!” – Sophie Samson, Florida

To be clear, there is no specific test, scan, or anything else of the sort that determines whether or not you should be taking CBD oil for pain. Let alone which is the best cbd for pain that will be effective for you. And since cannabis products are not yet recognized by the FDA, you can’t really go to your doctor either and have them recommend it. Until marijuana is FDA-approved as an analgesic (pain reliever), it cannot be prescribed by physicians.

How are you supposed to know?

So how are you supposed to know if you need CBD for pain? Well, ask yourself the following very simple questions:

  1. Are you in pain?
  2. Are your current medications working for you?

If the answer to these questions was ‘yes’ and ‘no,’ respectively, then some of the following best CBD oils for pain may be an option worth trying for you. Just remember - it is unlikely you'll get a recommendation from your physician to use CBD oil. You’re likely going to have to take it upon yourself to make the switch. If you're currently on medication, however, make sure you speak with a doctor first as CBD may interfere with the drugs you're taking.

Follow up on current studies

Whatever you end up doing, it should not be assumed that switching to CBD oil from a conventional medication will work for everyone. A randomized study consisting of 75 patients with chronic pain is currently being carried out in order to determine the clinical effects of CBD on pain management. Once the details of this study have been published (estimated for early 2020), we will know much more in regard to the realistic uses of CBD oil for pain relief.

Numerous studies have suggested that CBD may be able to help with pain management and other medical conditions. Fibromyalgia, for example, is a very painful condition that seems to respond positively to cannabis consumption. According to a 2011 study , cannabis-using fibromyalgia patients displayed a "statistically significant reduction of pain and stiffness, [as well as] enhancement of relaxation and an increase in somnolence and feelings of well-being."

Similar positive results have been shown in regard to the use of cannabidiol for other painful conditions. According to a publication in Therapeutics and Clinical Risk Management , for example, "CBD acts as an anti-inflammatory analgesic (pain-reliever) with CB 1 receptor antagonist and endocannabinoid modulating effects." Cannabinoids have been approved in Canada for well over a decade as neuropathic pain reducers in MS patients, as well as intractable pain reducers in cancer patients.

Dr. Ethan Russo, MD, has claimed that "cannabinoid analgesics have generally been well-tolerated in clinical trials … [and display] acceptable adverse event profiles." In other words, there is no shortage of evidence suggesting that CBD and other phytocannabinoids can offer natural plant-based pain therapy.

Additional Studies on the Use of CBD for Pain

A famous patient survey conducted in November 2018 by Project CBD stated that cannabis "appears to be an effective pain management tool with few negative side effects." The survey went on to say that "significant decreases" in opiate use have been observed among patients who consume cannabis.

In addition to this survey, Project CBD lists dozens of other published studies that have been carried out on the use of CBD for various therapeutic purposes. Over two dozen publications exist just on the use of cannabidiol for anxiety, for instance.

You are likely familiar with the dangers that prescription painkillers (and other pharmaceuticals) present. All too often these drugs can cause an overwhelming array of irritability, sleep disruption, digestive complications, and even thoughts of suicide.

One of the reasons CBD use for chronic pain has increased among patients is because it has far fewer side-effects than most prescription medications. The World Health Organization (WHO) , for instance, have come out and said that CBD is “not associated with any significant adverse public health effects," and that it is “not associated with abuse potential, does not induce physical dependence, [and] is generally well tolerated with a good safety profile.”

CBD is Safer Than Prescription Painkillers, But is it as Effective?

What is CBD oil effectiveness?

Few people realize that the U.S. Government holds a patent on cannabinoids as both antioxidants and neuroprotectants. With these pharmacological properties, it seems clear that natural cannabis compounds (like CBD) will be capable of helping with painful conditions like fibromyalgia, ALS, and multiple sclerosis - just to name a few.

Furthermore, the U.S. National Library of Medicine lists CBD in its PubChem database as a compound that boasts "analgesic (pain-relieving), anti-inflammatory, antineoplastic and chemopreventive activities." While data is lacking in terms of the efficacy of CBD compared to prescription painkillers, it is clear that the cannabis-based compound is the safer option.

As safe as CBD is, it is not without its potential side effects. Of course, these effects are largely minimal compared to the serious side effects associated with prescription opioids and other painkillers.

The best resource available in terms of highlighting CBD's side effects come from the clinical trials of Epidiolex (an FDA-approved cannabidiol drug used in the treatment of two rare forms of epilepsy). According to the trials, cannabidiol users may experience:

  • Somnolence
  • Decreased appetite
  • Diarrhea
  • Transaminase elevations
  • Fatigue, malaise, and asthenia
  • Rash
  • Insomnia, sleep disorder, and poor quality sleep
  • Infections

Furthermore, it has been suggested that CBD use may have an effect on liver health, but this is still under investigation. CBD is also known to interact with enzyme processes and drug metabolism, so it is important to speak with your doctor first if you are considering using CBD for pain along with other drugs.

Do you really think there's that much difference in quality between all these different CBD oil brands/products?

Absolutely. There are many steps in the process of making CBD products, and it’s imperative that each step be done with the utmost care. This requires spending a good bit of money, and some companies cut corners. That’s why some CBD products are no more effective than olive oil - because they may not even contain any CBD. Others may be inflammatory due to contamination by mold or other toxins. It’s best to use a CBD whose third-party testing results are on the company’s website to ensure you’re getting the amount of CBD they advertise and none of the things you don’t want.

What's the number one most important thing I should look for when trying to find a good CBD oil for my pain?

The most important thing to look for is the quality of the CBD oil and that it actually contains the amount of CBD you desire per dose. This information can be found via the third-party lab reports that each CBD company should have available on their website. The reports should show how much CBD (and any other cannabinoids present) are in the oil and whether there are any solvents or toxins present.

I've never used CBD oil for pain. Is there a specific dosage or milligram amount I should start out with?

This is best figured out by working with a cannabis/CBD expert. Many physicians are available for these types of consultations. The phrase “start low and go slow” is generally used when discussing CBD dosing, but working with a professional is the safest way to enact this trial process.

I take prescription medication. Should I really be concerned about taking CBD oil along with my med(s)?

Yes. CBD can interact with medications just like any other medication can. If you’re thinking that it’s less likely to interact because it’s all-natural, you should be aware that there are a number of medications that can’t be taken with grapefruit because even some natural substances can affect the metabolism of medications. This is why it’s always important to see your healthcare provider when starting a new medication, even CBD.

Do I really have to hold the oil under my tongue for 60+ seconds? Can't I just squirt it in and swallow?

You can, but the bioavailability may be increased and/or sped up if you allow it to sit under the tongue. This is because the oil enters the bloodstream directly once absorbed through the sublingual (under the tongue) tissue, which avoids it having to go through digestion before it can be metabolized and start affecting the body.

My doctor told me he/she didn't know enough about CBD to recommend it for my pain.

It’s always best to have a medical professional guide your usage of any medication, including CBD. Since CBD isn’t yet taught in medical schools, there are many doctors who are hesitant to recommend it. However, there are a number of qualified doctors who act as CBD consultants that can work in concert with your provider on finding a CBD regimen that works for you.

How many times a day should I take a dose?

This varies based on the amount of your initial dose, the condition you’re treating, and how your body metabolizes the CBD. This is why it is best to work with a medical professional specializing in CBD treatment to optimize your dosing schedule.

Do I have to worry about any side effects when taking CBD oil? Should I take it with food?

The most common side effects of CBD are nausea, diarrhea, loss of appetite, dry mouth, and fatigue/dizziness. These are rare but possible and are more likely at higher doses. Taking CBD with food doesn’t actually minimize the side effects, it can enhance bioavailability and the concentration of the CBD.

What is CBD oil produced from?

CBD oil extract should be extracted from the leaves, stalks, and flowers of hemp. It should not be made from the stems or seeds.

Is CBD oil legal?

This is still a murky subject. In November 2018, President Trump approved updates to the U.S. Farm Bill. Among other things, these updates legalized the production of hemp as a commercial crop. It also removed CBD from the DEA's list of Schedule 1 illicit substances.

Under these new laws, CBD products made from hemp are readily accessible in all 50 states. In the past, many assumed that CBD oil products from top brands were legal simply because they didn't contain the psychoactive properties of THC. While the THC content of hemp does not exceed 0.3%, this is not the reason for legality.

In fact, legal cases regarding CBD have been taken all the way to the U.S. Court of Appeals in recent years. Hemp Industries Assoc. v. DEA, decided in April 2018, determined that Section 7606 of the U.S. Farm Bill preempts the Controlled Substances Act (CSA). This decision implied that in the event of a contradiction between the CSA and the Farm Bill, the Farm Bill wins out.

Of course, now that CBD is no longer listed as a Controlled Substance, the determination of this case is irrelevant. All in all, the Farm Bill allows for the legal cultivation of industrial hemp, which is a source of CBD.

What about CBD from marijuana?

As we've discussed, CBD can also come from the marijuana plant. Therefore, whether or not CBD oil for pain is legal can be a question of which “version” of the cannabis plant it was sourced from. If it was sourced from industrial hemp, (which contains less than 0.3% THC), and the hemp was cultivated legally under regulations of the Farm Bill, then it is available in all 50 states.

However, if it was sourced from actual marijuana (i.e. cannabis that contains a higher THC content), then it is illegal in some states. Most of the best CBD oils for pain that you find in dispensaries in states like Colorado, California, and Washington (as well as other states where weed is legal) will have been extracted from marijuana plants -- not industrial hemp plants. Unfortunately, this means these products are not allowed to be sold online and shipped across state lines to “non-legal” states.

However, like we just mentioned CBD oil for pain management that has been sourced from industrial hemp grown under the farm bill is, in fact, available nationwide. The best CBD oil brands that we cover here on this site claim to extract their concentrates from U.S.-based industrial hemp supplies.

The important thing is that you have to be careful when selecting CBD oils. Since the cannabis industry is not FDA-regulated, there have been dozens of companies selling low-quality products with unreliable content labeling.

Do you need a doctors recommendation to purchase CBD oil?

If you are purchasing CBD that has been extracted from hemp, you do not need a doctors recommendation to purchase.

How does CBD work in the body?

CBD works by activating receptors and neurotransmitters through a network of cannabinoids called the endocannabinoid system (ECS).

Unlike THC, which binds directly to CB-1 receptors located in the brain, CBD works in the body by manipulating receptors throughout organ tissues, the immune system, the pain response system, the hormonal system, and other whole-body regulatory systems. CBD receptors have been found in virtually every cell and tissue type in the body. For this reason, CBD is believed to work on many aspects of human health and behavior - from the subcellular level to the whole-body level and beyond.

CBD is therapeutic in that it manipulates body systems at the cellular level and returns afflicted organ systems, tissue systems, and even chemical systems in the central nervous system back to a state of health and homeostasis. This is why it has been capable of treating conditions such as depression and anxiety, as well as chronic physical ailments such as pain, inflammation, arthritis, and more.

What does CBD help with?

Aside from two rare forms of epilepsy, the FDA does not recognize the medical use of CBD for any medical condition. That said, numerous reports have shown that the compound may have beneficial effects on a variety of conditions and ailments. Many have claimed that CBD oil helps them with the challenges of:

  • Alzheimer’s disease
  • Anorexia
  • Anxiety
  • Arthritis
  • Asthma
  • Chronic pain
  • Depression
  • Epilepsy (seizures)
  • Inflammation from various conditions
  • Insomnia
  • Multiple Sclerosis
  • Nausea (emesis)
  • Obesity
  • Post-Traumatic Stress Disorder (PTSD)

How do I use CBD oil for pain?

Be advised that there is no single right or wrong way to go about it. Many people end up using higher-strength products for pain than they do for things like anxiety, stress, or depression. The majority of today's best CBD oil manufacturers offer tinctures in three different “potencies.” These are usually in 100, 300, or 600 mg options. A lot of people start on a low dose with a 300 mg option, and work their way up from there. It is important to consult with the brand you are purchasing from before consumption.

The key is to effectively gauge exactly how much CBD oil it takes to start managing your pain. If you start off right away with a maximum dose of a 600 mg tincture, you will have no idea how much of the product it actually took to treat your condition. You'll also not know how much you wasted, which is important because you don't want to exceed dosage and end up developing a tolerance to the active cannabinoids.

If your intention is to help treat chronic pain, start out with a lower dose and proceed from there. If you notice effective results, you can downsize the dose or likewise up the dose until positive results are achieved. The key is to only increase your dosage in small increments so that you are able to pinpoint exactly how much CBD oil it takes to treat your condition. Be advised, though, that you should not exceed the recommended daily doses that are listed on the bottle. Also, consult with a physician if you plan on taking CBD with other medication.

Are there other options if you can't use CBD oil for pain?

Some people either can’t use CBD oil for pain (i.e. they may not want to hold the oil under their tongue before swallowing) or they simply haven’t found it to be effective. Fortunately, there are other options like topical CBD creams.

CBD topicals are one of the most popular choices for arthritis and other forms of localized pain and inflammation. Since the skin acts as a semi-permeable membrane, rubbing CBD-infused creams onto an affected area can be effective in terms of both pain and inflammation reduction.

Likewise, CBD gummies and other CBD edibles are a great option that people prefer over CBD oils for a variety of reasons (one of which is simply because they taste a lot better!). Lastly, vaping CBD oil with a vape pen has been another effective method of using cannabidiol as a pain relief therapy for some users.


Don't want to sit and read our best CBD oil for 2020 picks? Watch a quick summary via our video CBD oil countdown instead!

10 Best CBD Oil Brands for Pain Relief

So without further ado, here are the best CBD oils for pain relief based on quality, effectiveness, benefits and price. (Also note, all coupons have been tested and are currently functioning).


  • Full-spectrum extract, 99% pure
  • Potent, fast-acting results
  • 3rd party laboratory tested
  • No pesticides, solvents or chemical fertilizers


  • High potency oils are pretty expensive
  • No combo/bulk discounts

PureKana is a unique company that has been helping thousands of people located all across the U.S with its CBD oil drops. They have been featured on numerous major sites including Forbes and High Times , and are frequently voted as one of the Best CBD Oil brands on the market.

Unlike other CBD oils, PureKana really does excel in CBD oil extractions due to their unique CO2 extraction process which provides a near 99% pure CBD oil. PureKana Natural CBD Oil is an unflavored, dietary and nutritional supplement for increased health and vitality. It is extremely effective in helping to treat chronic pain, support recovery from exercise-induced inflammation, swelling, management of normal, everyday stresses, and to help promote healthy sleep cycles.

Key Features Include:

  • Organic products
  • Non-GMO
  • No pesticides, herbicides, solvents or chemical fertilizers
  • Non-psychoactive (only trace amounts of THC .03%)
  • 3rd party laboratory tested to ensure safety and potency
  • Products price range ($48.00 – $390.00) depending on potency
  • Free shipping on all products
  • Excellent return policy (30-day money-back guarantee)


  • Full-Spectrum Extract (Made in USA)
  • Incredible taste, near immediate effects
  • No artificial flavors or preservatives
  • 100% Natural and Organic


  • No CBD vape oils/vaping products
  • Does not offer CBD isolate oil

It’s been awhile since a CBD brand has turned our heads, but after receiving a few of their promotional sample products, Premium Jane simply blew us away.

One of our team members compared their 1,000 mg full-spectrum oral tincture to other CBD oils on the market and he said it was every bit as effective for his chronic back pain, with the effects actually seeming to last a little bit longer.

Here are some of the highlights of the Premium Jane lineup:

  • Sourced from CBD-rich hemp grown under the Kentucky Pilot Research Program
  • Incredible natural flavors produced from pure Citrus and Mint oil extracts
  • Full-Spectrum Extract packed with nutrients and more
  • 3rd party testing on all products and potencies
  • Prices range from $48-$125
  • Free shipping and supreme customer support


  • Appeals to health, exercise and fitness types
  • Great customer relations/customer service
  • Knowledgeable and willing to answer questions
  • All products are lab tested


  • No vape products available
  • Citrus flavor can be a little overwhelming

The main thing that is inherently clear when scouting out FabCBD is that they’ve made a pretty serious effort to develop a modern lifestyle brand. If you take a look at their website, everything from the web design to the brand labeling to the text they use screams modern and hip.

What does this mean in terms of the actual quality of their CBD oils? Well, you can be sure that if a brand invests this much in its image then it definitely creates a killer product. And for that reason we have ranked them number 3 on our best CBD oil list.

Even though FabCBD is still ranked below our superstar PureKana they have managed to establish themselves as a trustworthy brand with a premium product. All of their CBD products are sourced from organically grown Colorado hemp and extracted with pressurized CO2 technology, which is another sign that they’ve spared no expense in manufacturing a top-shelf oil.

In terms of price, they’re just a hair cheaper than the competition, with their 150mg tincture coming in at $39 and the 300mg at $59. They also have a popular 600mg oil, in three flavors (Citrus, Mint, and Natural). They also sell a 600mg muscle and joint topical cream for $64, and 750mg CBD chews for $54.

emphasis on brand appeal, and as such has garnered quite a large following of fitness and health fanatics. A good brand to look into if you are into health, fitness, and exercise. 


  • Chemical-free CO2 extraction process
  • 90-day money back guarantee
  • Certified hemp grown in the U.S
  • Prices start at just $29.99


  • Limited range of products and potencies
  • No edibles, vape oils, or vape products

CBD Pure hasn’t received the high-profile accolades as some of the other brands like PureKana and PremiumJane, but make no mistake – they manufacture one of best CBD tinctures on the market. Especially when discussing products that help to treat everyday pain.

Moreover, they use 3rd party lab testing to verify that every batch has perfect cannabinoid profiling, is pesticide-free, and is free of any harmful microorganisms or pathogens that may have been present as bacteria or fungi in the raw hemp material.

Here are the CBD oils that they currently have on offer:

  • 100 mg Hemp oil extract
  • 300 mg Hemp oil extract
  • 600 mg Hemp oil extract

Also, being a relatively small company you can expect that their customer service is second to none – if you have any questions at all about anything, you can get in touch with them. CBDPure offers a great product for a reasonable price ($24-$69)


  • Full-spectrum Extract
  • Derived from Non-GMO Hemp
  • Massive 66.6mg CBD per serving
  • Free shipping on orders over $75


  • CBD oils rarely discounted
  • 300mg is lowest potency option

While most CBD oil products offer up about 5-7 mg of CBD per serving (or even less than that), Hemp Bombs’ max-strength sublingual tinctures provide a massive 60 mg dose in a single dropper. For many people, this will be a more than sufficient amount to help relieve symptoms like generalized anxiety and pain.

Of course, though, they offer less potent oils than that, with a product lineup that ranges from 300 mg CBD per bottle to 4,000 mg. Naturally the 4,000 mg option is the most expensive (this is the one that provides the “bomb” 60 mg dose), as it currently sells for $299. For long-term pain and anxiety relief, though, it may be well worth it if it is effective for you and helps replace your regular meds.

Hemp Bombs is based in Tampa, Florida, and in addition to focusing on the purity and therapeutic effectiveness of their products, are dedicated to establishing themselves as a top brand in the industry with a specific target audience. One of our personal favorite products of theirs is the flavored CBD vape liquids, which are some of the best-tasting CBD vape juices we’ve ever had.


  • One of the top-selling USA brands
  • Developed by world famous Stanley Brothers
  • 15% off for military veterans
  • Offer specific CBD oil for dogs


  • More expensive than comparable products
  • Limited range of products

Charlotte's Web is currently one of the top CBD hemp brands in the U.S and is constantly featured on top authority websites such as The Wall Street Journal, Time and The Huffington Post. What started off as a hemp strain packed with CBD to help a girl named Charlotte Figi, soon turned into an empire. Today, Charlotte's Web, formerly known as CWhemp offers a wide range of high-quality products including oils, capsules and even CBD gummies. Want to learn more check out our Charlotte’s Web CBD oil Review .

Key Features include:

  • As a whole plant extract, CW Hemp Extract in MCT contains not only 500mg of CBD per bottle but also incorporates other cannabinoids, such as CBC, CBG, CBN, Amino Acids, Terpenes and Phytonutrients found in our proprietary hemp strains.
  • Charlotte’s Web hemp oil extract contains the highest-quality hemp oil, rich in natural CBD
  • Product price range – $39.99-$299.96


  • Huge selection of CBD dabs/isolates
  • Great CBD vape selection
  • Low price options for first time CBD users
  • 99% pure CBD isolate


  • Not known for their full-spectrum products
  • Does not state source location of hemp

If you’re looking for maximum potency CBD oil for pain management, then CBDistillery’s range of tinctures should probably be at the top of your list. They use a 99% pure CBD isolate that customers have used on everything from stress to insomnia to chronic pain.

Moreover, the folks at CBDistillery are renowned as being some of the most passionate, knowledgeable, and honest in the industry. They are completely transparent and have nothing to hide in either their products or their manufacturing processes.

Check out what people had to say about CBDistillery by reading our comprehensive CBDistillery Review


  • Premium broad spectrum CBD products
  • Unique extraction process that creates consistency
  • Lab tested products to provide a premium product
  • 30-day money-back guarantee on all products


  • Not the cheapest brand on the market
  • Could have an easier purchasing process

With so many brands on the market it's often hard to come across a reputable high-quality one. Joy Organics has distinguished itself as one of the top in the industry and due to this reason we’ve ranked them number 8 on our best CBD oil list. What started off as a small-run family business has in recent years turned into a CBD powerhouse.

Apart from having a huge online presence, Joy Organics also has 3 physical locations; Austin Texas, Deer Park, Illinois and Fort Collins Colorado.

Joy Organics is one of those brands that believe in variety and therefore on their site you’ll find a wide range of products, from CBD oils to CBD Bath bombs and even energy drinks. Their products are second to none and they claim that all their store products contain zero harsh chemicals and have an astonishing absorption rate. Unlike other brands they have created broad spectrum products that are premium grade. The best part about this brand is that they stand behind their products by offering a 30-day money-back guarantee.

If you are looking for a quality product then JoyOrganics is the place to go.

Check out their full JoyOrganics CBD Review Here


  • Medicinal grade hemp extract
  • Delicious CBD oil candy edibles
  • Fast shipping + great customer service
  • Over 5 Years Experience


  • Prices start at $64
  • Only two potencies available

Some people say that CBD Essence’s tincture is the absolute best CBD oil for pain and anxiety. And this may just be true given that they offer and “advanced and natural formula” based off unique extraction processes. Also, a team of pharmacists helps to employ state-of-the-art technology in formulating the tincture.

CBD Essence's range of CBD oils are what’s called “full-spectrum.” Basically, this means that in addition to the active CBD component they contain other important ingredients from the cannabis plant (such as terpenes and flavonoids). However, it’s important to understand that their products are 100% THC-free, meaning they don’t produce any high at all.

In addition to their range of tinctures (which come in 150, 300, and 600 mg options), they also offer hemp edibles, capsules, pastes, vape liquids, topicals, and pet care products. Price range: $62-$204 (depending on the potency).

Check out their full range of CBD options on their official site or read the complete CBD Essence Review


  • One of industry's most trusted names
  • 5% of every purchase goes to charity
  • Sustainable seed-to-shelf operation
  • Sourced from 100% certified organic hemp


  • Not many flavors to choose from
  • Not the cheapest products on the market

Elixinol has a wide range of products, but their CBD Tincture does the trick. It’s the cream of the crop regarding CBD oils and that reflects in its price. One dropper (1mg) from the 300 series contains 10mg of CBD. This allows you to get precise amounts of CBD and no guess work is required. Elixinol has received numerous awards for their products and extraction process.

Key Features include:

  • Highest strength tincture
  • Available in Cinnamint & Natural flavor
  • Full-spectrum Cannabinoid extract
  • Organic hemp CO2 extract tincture
  • Products price range ($39-$249)

Where to Start and Our Best CBD Oil for Pain Relief?

We tend not to play favorites but if we had to choose just one, we would check out our #1 pick PureKana. Not only have they managed to assist thousands of patients, but their customer support and product is top of the range.

  • Official Website:
  • 15% Coupon Code: 15KANA

Other CBD oil brands have high-quality products, but our choice came down to variety, potency, and price. Whichever you choose to go for, though, know that all of the companies above have an outstanding store and offer a wide range of effective products, from CBD oils to Terps and even CBD creams. Plus, most have a 100% money-back guarantee policy, which is quite nice!

And here are our...

  • Full range of CBD
  • Nationwide fast and reliable delivery
  • Highly concentrated extraction process
  • Lab results for all products
  • Full-spectrum extract, 99% pure
  • Potent, fast-acting results
  • 3rd party laboratory tested
  • No pesticides, solvents or chemical fertilizers
  • Full-Spectrum Extract (Made in USA)
  • Incredible taste, near-immediate effects
  • No artificial flavors or preservatives
  • 100% Natural and Organic
  • Chemical-free CO2 extraction
  • 90-day money-back guarantee
  • Certified U.S grown hemp
  • Excellent customer support

CBD oil and pain: A review by Dylan Baker

This article provides a wealth of practical information for the individual considering CBD as an adjunctive or alternative treatment for pain and or anxiety. CBD works in the body by manipulating receptors throughout organ tissues, the immune system, the pain response system, the hormonal system, and other systemic regulatory systems.

CBD oils have not been reviewed or approved by the FDA for the treatment of these conditions. However, there is a wealth of literature (both anecdotal and research-related) that exists describing CBD's safety and effectiveness. As discussed in this article, the potential new adopter must be mindful of several important items.

First, only those products that are sourced from industrial hemp will be considered legal in all states. One must be careful if the product you choose is sourced from the marijuana plant, as those products may contain THC levels above the legal limit in your given state.

Secondly, all products are NOT created equal – they differ significantly in strength, absorption, and elimination by the body and in the manner in which they are formulated. One should be mindful of the differences in doses available for each of these products, starting at a low or moderate dose and increasing as needed in order to find the lowest dose that provides the desired relief. In this way, one can individualize usage to maximize effectiveness while minimizing risk - a proper goal for the use of all medicinals.

The time it takes for CBD oil to take effect depends on how you take it. Oils take longer to work than inhaled CBD and topicals. CBD oils take about the same time to have an effect as CBD edibles do because most of the oil ends up being metabolized through the same pathways as edibles. Both of them can be felt to start working at somewhere between 30 and 90 minutes after ingestion. Many advise that if when consuming a CBD oil, you should put it under your tongue for 30-90 seconds to help absorption; however, only a small fraction of the product in a traditional oil gets absorbed sublingually even when using this method, so while the amount that does get absorbed sublingually may be noticeable sooner, the majority of the effects will still be felt in that 30 to 90-minute range.

Dosing of CBD oil is very individualized. Many factors affect how much CBD will be necessary to address a person’s pain, including their size, metabolism, history of CBD use, and the cause of the pain. For example, pain from autoimmune conditions may take higher doses to address than pain from a sore muscle. Most specialists recommend the old adage of ‘start low and go slow’ when trying to find a CBD oil dose that works. When titrating, know that sometimes it takes a couple of weeks for some of the cannabinoid levels to build up in the fat cells. Once that happens, there will be a slow but more continuous release of CBD that can help with pain on a more stable basis.

There are many ways to take CBD for pain. Research has shown that topical CBD can be effective in arthritis pain, and for those without respiratory concerns, vaping can provide the quickest relief. However, CBD oil has the advantage of lasting the longest in the system and therefore needing the least doses per day. Once you have decided what dose of CBD oil best controls your pain, notice when the effects start to wear off and that is when you should take another dose. Most people who use CBD for pain dose twice a day, as that generally covers most of the day, as its effects last for an average of 4 to 6 hours, though that can vary widely based on a number of factors, including dose taken and the user’s metabolism.

If you’re in the US you can pick up CBD oil for pain online, as long as the CBD you’re interested in is from hemp, meaning it has a THC content of less than .3%. If you want a CBD oil with more THC, then you’d have to either live in a state where cannabis is legal or have a medical cannabis card and get it via that route. (NOTE: to MB staff - I have no idea what the laws are for purchasing in other countries…)

The effects of CBD, if inhaled, can be felt for around two hours. CBD oil, thanks to the way it’s metabolized in the body, enacts its effects for a longer period, around four to six hours. You may also notice that CBD works better for the longer period of time in which you take it, and this can be due to stores of CBD that are kept in the fatty tissues of our bodies getting released even outside of the time that one is taking CBD, so effects can seem even longer-lasting after a period of use has built up CBD levels in the body.